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Thorne Research, Methyl-Guard Plus, 90 Capsules

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Thorne Research, Methyl-Guard Plus, 90 Capsules

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Thorne Research, Methyl-Guard Plus, 90 Capsules

In Stock
  • Expiration Date: February 2019
  • Shipping Weight:
    0.14 kg
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  • Product Code: THR-78901
  • UPC Code: 693749789017
  • Dimensions:
    11.2 x 6.1 x 6.1 cm , 0.11 kg
    Switch to Imperial units
Frequently Purchased Together
Product Overview


  • Methylation Factors
  • Dietary Supplement
  • Heart / Vessels
  • Mood
  • Gluten Free

Supports heart, blood vessel, brain, and bone health by enhancing healthy methylation.

Methyl-Guard Plus provides 5-MTHF (active folate) and the active, tissue-ready forms of vitamins B2, B6, and B12 to support healthy methylation for cardiovascular, cognitive, and bone health.

Methylation is key to keeping homocysteine levels in check, as well as for facilitating multiple biochemical processes involving neurotransmitter synthesis, detoxification, cardiovascular health, eye health, muscle health, bone health, and redox balance. Maintaining a desirable level of homocysteine in the blood has joined healthy cholesterol and triglyceride levels as leading biomarkers for the maintenance of good cardiovascular health. Preventing an undesirable homocysteine level is also associated with the maintenance of bone, female reproductive, cognitive, and neurological health. Methyl-Guard Plus supports methylation and promotes healthy homocysteine levels with betaine (trimethylglycine), 5-MTHF (the active form of folate), riboflavin 5'-phosphate (the active form of vitamin B2), pyridoxal 5'-phosphate (the active form of vitamin B6), and methylcobalamin (an active form of vitamin B12).

Suggested Use

Take 1-3 capsules daily or as recommended by a health-care practitioner.

Other Ingredients

Hypromellose (derived from cellulose) capsule, calcium citrate, calcium laurate.


Tamper evident: Use only if bottle is sealed.

If pregnant, consult your health-care practitioner before using this product.

Store tightly sealed in a cool, dry place.

Supplement Facts
Serving Size: Three Capsules
Servings Per Container: 30
  Three Capsules Contain: %DV
Riboflavin (as Riboflavin 5'-Phosphate Sodium) 90 mg 6,923%
Vitamin B6 (as Pyridoxal 5'-Phosphate) 45 mg 2,647%
Folate (3 mg as L-5-Methyltetrahydrofolate† from L-5-Methyltetrahydrofolic Acid, Glucosamine Salt) 5 mg DFE 1,250%
Vitamin B12 (as Methylcobalamin) 3 mg 125,000%
Betaine Anhydrous (Trimethylglycine) 1.8 g *
*Daily Value (DV) not established.
† This product uses Gnosis S.p.A.'s L-5-Methyltetrahydrofolic Acid, Glucosamine Salt (Quatrefolic).
iHerb Customer Reviews

Excellent for MTHFR issues

Posted by Happichique on February 8 2018 | Verified Purchase

I have tested positive for the double MTHFR genetic problem. I have done a lot of research (in step with my Naturopath) and this product is THE best providing ample support for this genetic abnormality. If I miss taking a tablet, I immediately know as my hands and feet get the 'tingles' which is so uncomfortable. If you are considering taking a supplement for MTHFR problems please do it with the advice of your naturopath or doctor as there are varying doses

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Methyl Guard Plus

Posted by iHerb Customer on February 3 2018 | Verified Purchase

Excellent product!

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Easy to order.

Posted by iHerb Customer on December 5 2017 | Verified Purchase

Product is just what I expected.. Delivery time is more of an issue. . Could be because of Christmas.

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Product Review

Posted by iHerb Customer on October 30 2017 | Verified Purchase

Been using for a long time due to gene mutation restricting absorption of B Vitamins.

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This methylated product ensures absorption of nutrients

Posted by iHerb Customer on September 18 2017 | Verified Purchase

Six years ago blood tests revealed that I had a fault with the MTHFR gene. I am heterozygous (C/T) at position 677 normal position is (C) and heterozygous (A/C) at position 1298 normal position is (A) I have been taking Methyl Guard since diagnoses and have felt great ever since. I do moderate the dosage, down or up according to directions. to keep on an even keel.

Thanks for your feedback!