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Now Foods, SAM-e (S-Adenosyl-L-Methionine), 400 mg, 30 Tablets (Discontinued Item)

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Now Foods, SAM-e (S-Adenosyl-L-Methionine), 400 mg, 30 Tablets (Discontinued Item)

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Now Foods, SAM-e (S-Adenosyl-L-Methionine), 400 mg, 30 Tablets (Discontinued Item)

Out of Stock - Discontinued
400 mg
400 mg
200 mg
30 Tablets
30 Tablets
60 Tablets
  • Shipping Weight:
    0.27 kg
    Switch to Imperial units
  • Product Code: NOW-00139
  • UPC Code: 733739001399
  • Package Quantity: 30 Tablets
  • Dimensions:
    5.1 x 5.1 x 9.7 cm , 0.16 kg
    Switch to Imperial units
Frequently Purchased Together
Product Overview


  • Nervous System Support
  • Supports Emotional Well-Being
  • Supports Joint Health
  • Enteric Coated
  • GMP Quality Assured
  • A Dietary Supplement
  • Vegetarian/Vegan

SAMe (S-adenosylmethionine),a compound native to the body, is a critical component of many biochemical reactions, including those that affect brain biochemistry and joint health. Numerous studies have indicated that SAMe can help to temporarily alleviate minor joint discomfort resulting from overexertion or stress. In addition, because SAMe is also necessary for the synthesis of neurotransmitters, it plays an important role in mood support. NOW SAMe is enteric-coated, which makes it very well tolerated and protects it from degradation.

Suggested Use

As a dietary supplement, take 1 tablet 2 to 4 times daily, preferably on an empty stomach.

Other Ingredients

Cellulose, croscarmellose sodium, magnesium stearate (vegetable source), silica, stearic acid (vegetable source), ascorbic acid, citric acid and enteric coating (cellulose, triethyl citrate, methacrylic acid).

Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish or tree nut ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.


Do not eat freshness packets. Keep in bottle.

For adults only. Individuals with bipolar (manic) depression and those with anxiety disorders should not take SAMe unless under professional medical supervision. Consult physician if pregnant/nursing, taking medication, or have a medical condition. Keep out of reach of children.


While iHerb strives to ensure the accuracy of its product images and information, some manufacturing changes to packaging and/or ingredients may be pending update on our site. Although items may occasionally ship with alternate packaging, freshness is always guaranteed. We recommend that you read labels, warnings and directions of all products before use and not rely solely on the information provided by iHerb.
Supplement Facts
Serving Size  1 Tablet
  Amount Per Serving %Daily Value
SAMe (S-Adenosyl-L-Methionine)
(from 800 mg of S-Adenosyl-L-Methionine Disulfate
400 mg *
* Daily Value not established.
iHerb Customer Reviews


Posted by TMarchev on December 12 2015 | Verified Purchase

Nice work to me !

Thanks for your feedback!


Posted by iHerb Customer on March 19 2015 | Verified Purchase

very good

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Helped a lot!

Posted by iHerb Customer on August 23 2014 | Verified Purchase

Helped a lot!

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Used for depression

Posted by iHerb Customer on August 13 2014 | Verified Purchase

My husband has been taking this herb for depression, they were recommended by his doctor. He felt a difference instantly. Postage was extremely fast and we have been happy with iherb processing. :)

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good for mental health and liver!

Posted by iHerb Customer on October 12 2013 | Verified Purchase

This stuff is great for your mood and your health!

Thanks for your feedback!